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CasNo: 71751-41-2
Molecular Formula: C48H72O14;C47H70O14
Appearance: white powder
Bio-pesticides |
Abamectin, is a member of the avermectin family and is a natural fermentation product of soil dwelling actinomycete Streptomyces avermitilis. Abamectin differs from ivermectin, the popular member of the avermectin family, by a double bond between carbons 22 and 25. Abamectin is a kind of 16-membered ring macrolide compound which was first developed by the Kitasato University in Japan and Merck Company (United States). It has insecticidal, acaricidal, and nematicidal activity. According to the pundits’ prediction, the 21st century will be the century of biological pesticides. It is reported that the European bio-pesticides sales increased from 100 million dollar (1997) to 160 million dollars in 2004. Abamectin is the most popular and highly competitive novel biological pesticide in currently bio-pesticide market. |
Uses |
Abamectin is used by the agricultural community to control insects and mites on a large range of crops such as: citrus, pears, alfalfa, nut trees, cotton, vegetables, and ornamental. When abamectin is applied to crops and orchards, it is absorbed by the foliage and affects the insect when it eats the leaves. Abamectin, widely used as a veterinary anthelmintic, medicine against a variety of animal parasites and insects, can runoff from the sites of application and becomes an aquatic pollutant. |
Analysis Methods |
High Performance Liquid Chromatography. |
Reactivity Profile |
A lactone. |
Hazard |
A poison by ingestion. Moderately toxic by inhalation and skin contact. |
Mechanism of Action |
Abamectin acts on both glutamate-gated chloride channels (GluCls) and 纬-aminobutyric acid (GABA)-gated chloride channels in arthropods, leading to paralysis of the target organisms. |
Definition |
Any of a group of broad spectrum antiparasitic antibiotics produced by the actinomycete, Streptomyces avermitilis. |
Who Evaluation |
Evaluation year: 1998 |
InChI:InChI=1/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12+,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1
The aim of this study was to identify the toxicity of abamectin on bacteria, algae, daphnids, and fish. An extremely high toxicity of avermectin to the survival and reproduction of Daphnia magna was observed in 21-day exposure tests. Zebrafish and the algae Scenedesmus subspicatus are less sensitive to avermectin. The compound is expected to have adverse effects on the aquatic environment due to its high toxicity, even at very low concentrations, to daphnids and to fish.
Abamectin undergoes rapid photolysis under a number of different conditions. Photolysis occurs when abamectin is exposed to light in water, on soil particles, or as a thin film on either …
This study aimed at determining the toxicity of avermectins to soil invertebrates in soil and in faeces from recently treated sheep. Abamectin was more toxic than doramectin.