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CasNo: 2498-50-2
Molecular Formula: C7H11Cl2N3
Appearance: white to yellowish fine crystalline powder
Preparation |
4-Aminobenzamididine dihydrochloride is obtained by cyanation, addition, amination and reduction of 4-nitrobenzoic acid. |
Application |
4-Aminobenzamidine dihydrochloride can be used to synthesize:Orally active fibrinogen receptor antagonists based on benzamidines.Benzamidine derivatives that are selective and potent serine protease inhibitors.Novel pyrrolo [3,2-c] quinolines that are structural analogs of topoisomerase inhibitors such as coralyne and fagaronine.Synthesis of a selective inhibitor of PRMT1 (SKLB-639) |
InChI:InChI=1/C7H9N3/c8-6-3-1-5(2-4-6)7(9)10/h1-4H,8H2,(H3,9,10)/p+1
The invention discloses a novel preparat...
Hepsin is a membrane-anchored serine pro...
The invention relates to the technical f...
Two novel series of diaryl urea derivati...
4-nitrobenzamidine
4-aminobenzamidine dihydrochloride
Conditions | Yield |
---|---|
4-nitrobenzamidine; With iron; acetic acid; In ethanol; water; at 60 - 80 ℃; for 4h;
With hydrogenchloride; In ethanol; water; Reagent/catalyst;
|
94.7% |
N-(4-cyanophenyl)acetamide
4-aminobenzamidine dihydrochloride
Conditions | Yield |
---|---|
N-(4-cyanophenyl)acetamide; With sodium amide; In dimethyl sulfoxide; at 20 - 80 ℃; for 1.5h; Large scale;
With hydrogenchloride; In ethanol; dimethyl sulfoxide; at 0 ℃; for 1.5h; pH=3 - 4; Solvent; Reagent/catalyst; Temperature; Large scale;
|
97.8% |
4-Aminobenzonitrile
4-nitrobenzonitrile
4-nitrobenzimidic acid methyl ester
4-nitrobenzamidine
2-<2-(4-aminophenyl)-4-imidazolyl>ethanamine
4-<<4-(aminoiminomethyl)phenyl>amino>-4-oxobutanoic acid
4-[N-(benzyloxycarbonyl)-aminoiminomethyl]aniline
tert-butyl [(4-aminophenyl)(imino)methyl]carbamate